Maudsley精神科处方指南:英文版

Preface
Acknowledgements
Notes on using The Maudsley Prescribing Guidelines
List of abbreviations
Chapter 1 Plasma level monitoring of psychotropic drugs
Interpreting sample results
Acting on clozapine plasma concentration results
Interpreting post-mortem blood concentrations
Chapter 2 Schizophrenia
ANTIPSYCHOTIC DRUGS
General introduction
General principles of prescribing
Minimum effective doses
Quick reference for licensed maximum doses
Equivalent doses
High？dose antipsychotics: prescribing and monitoring
Antipsychotic prophylaxis
Combined antipsychotics
Negative symptoms
Monitoring
Relative adverse effects ？ a rough guide
Treatment algorithms for schizophrenia
First？generation antipsychotics？place in therapy
Omega？3 fatty acid (fish oils) in schizophrenia
New and developing drugs to treat schizophrenia
NICE guidelines for the treatment of schizophrenia
Antipsychotic response ？ to increase the dose, to switch,to add or just wait ？ what is the right move?
Antipsychotic long？acting injections
Depot antipsychotics ？ pharmacokinetics
Management of patients on long？term depots
Aripiprazole LAI
Olanzapine LAI
Paliperidone palmitate LAI
Risperidone LAI
ANTIPSYCHOT ICS ？ ADVERS E EFFECTS
Extrapyramidal side？effects
Akathisia
Weight gain
Treatment of drug？induced weight gain
Tardive dyskinesia
Neuroleptic malignant syndrome
Catatonia
QT prolongation
Dyslipidaemia
Diabetes and impaired glucose tolerance
Hypertension
Hyponatraemia
Hyperprolactinaemia
Sexual dysfunction
Pneumonia
Switching antipsychotics
REFRACTORY SCHIZOPHRENIA AND CLOZAPINE
Clozapine ？ dosing regimen
Optimising clozapine treatment
Alternatives to clozapine
Re？starting clozapine after a break in treatment
Initiation of clozapine for community？based patients
CLOZAPINE ？ ADVERS E EFFECTS
Common adverse effects
Clozapine: uncommon or unusual adverse effects
Clozapine: serious haematological and cardiovascular adverse effects
Clozapine？indu