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- ISBN:9787313180957
- 装帧:一般胶版纸
- 册数:暂无
- 重量:暂无
- 开本:25cm
- 页数:437页
- 出版时间:2017-11-01
- 条形码:9787313180957 ; 978-7-313-18095-7
内容简介
本书整合了基础生物信息学、临床信息学、统计遗传学的综合性研究领域, 通过分析大量的临床数据, 理解疾病发生发展的分子基础, 并形成系统性的临床应用知识体系。
目录
Part I Computer-Aided Drug Discovery
1 Drug Discovery
Geetha Ramakrishnan
2 Translational Bioinformatics and Drug Discovery
Pramodkumar Pyarelal Gupta
3 Translational Research in Drug Discovery and Development
Neha Arora, Pawan Kumar Maurya, and Puneet Kacker
4 Exploring the Potential of Herbal Ligands Toward Multidrug-Resistant Bacterial Pathogens by Computational Drug Discovery
Sinosh Skariyachan
Part II Protein-Ligand Interactions and Drug Development
5 The Progress of New Targets of Anti-HIV and Its Inhibitors
Ke Z. Wu and Ai X. Li
6 Recent Studies on Mechanisms of New Drug Candidates for Alzheimer's Disease Interacting with Amyloid-β Protofibrils Using Molecular Dynamics Simulations
Huai-Meng Fan, Qin Xu, and Dong-Qing Wei
7 Homology Modelling, Structure-Based Pharmacophore Modelling, High-Throughput Virtual Screening and Docking Studies of L-Type Calcium Channel for Cadmium Toxicity
Madhu Sudhana Saddala and A. Usha Rani
8 Natural Compounds Are Smart Players in Context to Anticancer Potential of Receptor Tyrosine Kinases:
An In Silico and In Vitro Advancement
Pushpendra Singh, Shashank Kumar, and Felix Bast
Part III Omics for Precision Medicine
9 Genome-Wide Association Studies: A Comprehensive Tool
to Explore Comparative Genomic Variations and Interactions
Aruni Wilson
10 A Survey of Bioinformatics-Based Tools in RNA-Sequencing
(RNA-Seq) Data Analysis
Pall**i Gaur and Anoop Chaturvedi
11 Epigeics and Its Role in Human Cancer
Utkarsh Raj and Pritish Kumar Varadwaj
12 Methods for Microhiome Analysis
Kalibulla Syed Ibrahim and Nachimuthu Senthil Kumar
13 Pharmacogenomics: Clinical Perspective, Strategies,and Challenges
Dev Bukhsh Singh
Part IV Biostatistics, Bioinformatics, and System Biology Approaches to Complex Diseases
14 Computational Network Approaches and Their Applications for Complex Diseases
Ankita Shukla and Tiratha Raj Singh
15 Bioinformatics Applications in Clinical Microbiology
Chao Zhang, Shunfu Xu, and Dong Xu
Part V Bioimaging and Other Applications of Informatics Techniques in Translational Medicine
16 Artificial Intelligence and Automatic Image Interpretation in Modern Medicine
Costin Teodor Streba, Mihaela Ionescu, Cristin Constantin Vere, and Ion Rogoveanu
17 Computation in Medicine: Medical Image Analysis and Visualization
Adekunle Micheal Adeshina
Index
1 Drug Discovery
Geetha Ramakrishnan
2 Translational Bioinformatics and Drug Discovery
Pramodkumar Pyarelal Gupta
3 Translational Research in Drug Discovery and Development
Neha Arora, Pawan Kumar Maurya, and Puneet Kacker
4 Exploring the Potential of Herbal Ligands Toward Multidrug-Resistant Bacterial Pathogens by Computational Drug Discovery
Sinosh Skariyachan
Part II Protein-Ligand Interactions and Drug Development
5 The Progress of New Targets of Anti-HIV and Its Inhibitors
Ke Z. Wu and Ai X. Li
6 Recent Studies on Mechanisms of New Drug Candidates for Alzheimer's Disease Interacting with Amyloid-β Protofibrils Using Molecular Dynamics Simulations
Huai-Meng Fan, Qin Xu, and Dong-Qing Wei
7 Homology Modelling, Structure-Based Pharmacophore Modelling, High-Throughput Virtual Screening and Docking Studies of L-Type Calcium Channel for Cadmium Toxicity
Madhu Sudhana Saddala and A. Usha Rani
8 Natural Compounds Are Smart Players in Context to Anticancer Potential of Receptor Tyrosine Kinases:
An In Silico and In Vitro Advancement
Pushpendra Singh, Shashank Kumar, and Felix Bast
Part III Omics for Precision Medicine
9 Genome-Wide Association Studies: A Comprehensive Tool
to Explore Comparative Genomic Variations and Interactions
Aruni Wilson
10 A Survey of Bioinformatics-Based Tools in RNA-Sequencing
(RNA-Seq) Data Analysis
Pall**i Gaur and Anoop Chaturvedi
11 Epigeics and Its Role in Human Cancer
Utkarsh Raj and Pritish Kumar Varadwaj
12 Methods for Microhiome Analysis
Kalibulla Syed Ibrahim and Nachimuthu Senthil Kumar
13 Pharmacogenomics: Clinical Perspective, Strategies,and Challenges
Dev Bukhsh Singh
Part IV Biostatistics, Bioinformatics, and System Biology Approaches to Complex Diseases
14 Computational Network Approaches and Their Applications for Complex Diseases
Ankita Shukla and Tiratha Raj Singh
15 Bioinformatics Applications in Clinical Microbiology
Chao Zhang, Shunfu Xu, and Dong Xu
Part V Bioimaging and Other Applications of Informatics Techniques in Translational Medicine
16 Artificial Intelligence and Automatic Image Interpretation in Modern Medicine
Costin Teodor Streba, Mihaela Ionescu, Cristin Constantin Vere, and Ion Rogoveanu
17 Computation in Medicine: Medical Image Analysis and Visualization
Adekunle Micheal Adeshina
Index
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