
包邮方法与技术-神经科学百科全书-上-5

- ISBN:9787030280855
- 装帧:暂无
- 册数:暂无
- 重量:暂无
- 开本:16开
- 页数:592页
- 出版时间:2010-08-01
- 条形码:9787030280855 ; 978-7-03-028085-5
本书特色
《神经科学百科全书5:方法与技术(上导读版)》是由科学出版社出版的。
目录
节选
《神经科学百科全书5:方法与技术(上导读版)》原书篇幅巨大,为所有神经科学百科全书之首。由来自世界各地的2400多位专家撰稿人合力打造,覆盖了神经科学全部主要领域。书中每个词条在收入书中之前均经过顾问委员会的同行评议,词条中均含有词汇表、引言、参考文献和丰富的交叉参考内容。主编为著名神经科学家、美国神经科学学会前主席LarryR Squire内容平易.本科生即可读懂。深度和广度独一无二.足可满足专家学者的需要。导读版精选原书中的部分主题,按内容重新编排,更适合国内读者购买和阅读。
相关资料
Mice pose advantages over other species,such as rats,dogs,pigs,or primates,in several aspects:(1)It ISrelatively easy to house large numbers of them;(2)the mouse genome is better characterized than that of anyother mammaI except humans;(3)many geneticallyaltered transgenic knockout and knockin lines andgenetically characterized mouse strains are availablefor crossbreeding and further genetic analysis;(4)cognitive studies can be done in appropriate strains of mice,such as C5786/SJL and 129S6,making the mespecially relevant to the study of AD;and(5)studies in invertebrates,while useful,willlack some relevance in pharmacological studies and pathogenic in vestige.Tions To create transgenic mice with salient features of AD.investigators must take care in several aspects of design and development.The most important factors are the selection of the gene or gene variant to be expressed,the promoter driving transgene expression,the background strain of the mice. and the levels and distribution of transgenic protein expression achieved in the brain.The mouse lines with the most robust neuropathological phenotypes have been developed using the method of pronuclear microinjection oftransgenes into fertilized ocytes(Figure 1).B0th wildtype and variant human APP and tau genes have been used to generate mice that develop neuropathology related to AD.Transgenes containing mutations linked to aut osomaI dominant AD or FDTP generate morerobust neuropathology than transgenes encoding wild-type genes.Although mutations in presenilin一1 and presenilin.2 genes lead to early-onset ADin humans,mice expressing presenilin gene variants do not develop neuropathology per 5e.In the presence of human APP transgenes,howeve the presenilin gene variants accelerate plaque deposition in trans'genic mice.
-
急诊科里的一千零一夜
¥19.6¥58.0 -
内外伤辨惑论-局方发挥
¥1.9¥5.0 -
小儿推拿秘旨
¥3.3¥9.0 -
活幼心书
¥5.6¥15.0 -
格致余论
¥2.2¥6.0 -
临床常用百药精解-国医精粹口袋书系
¥11.2¥32.0 -
诊宗三昧
¥3.1¥6.0 -
医路向前巍子给中国人的救护指南
¥26.8¥68.0 -
鲁府禁方
¥5.6¥15.0 -
联袂药性赋白话解-国医精粹口袋书系
¥6.3¥18.0 -
脉因证治
¥5.3¥13.0 -
笔花医镜
¥3.8¥8.0 -
四诊扶微
¥5.8¥16.0 -
中医入门必背歌诀
¥12.4¥38.0 -
本草纲目
¥24.9¥76.0 -
中医诊断全书
¥18.7¥59.0 -
本草中国
¥34.8¥58.0 -
黄帝内经鉴赏辞典(文通版)
¥9.0¥28.0 -
成方切用
¥19.5¥39.0 -
系统解剖学
¥44.4¥79.0