医学遗传学 MEDICAL GENETICS(英文版)(留学生与双语教学用)

Chapter 1 Introduction

1.1 Genetics

1.2 Genetic Diseases

Summary

Exercises

Chapter 2 Mendel's Laws of Inheritance

2.1 Gregor Mendel （1822-1884）

2.2 Mendel's Experiments on Pea Plants

2.3 Relative Knowledge About Mendel's Experiments

2.4 Mendel's Laws

Summary

Exercises

Chapter 3 The Bases of Genetics

3.1 Molecular Structure of a Gene

3.2 DNA Sequences

3.3 Regulahon of Gene Expression

3.4 Genetic Imprinting

3.5 Mutation

3.6 Somatic and Germline Mutation

3.7 "Loss of Funchon Mutahon" and "Gain of Function Mutahon"

3.8 Molecular Basis of Gene Mutahon （Point Mutation）

3.9 Mutagens

Summary

Exercises

Chapter 4 Inheritance Pattern of Single Gene Disorders （Monogenic Inheritance）

4.1 Monogenic Inheritance （Mendelian）

4.2 Pedigree Chart

4.3 Autosomal Dominant Inheritance （AD）

4.4 Case Study

4.5 Comment

4.6 Autosomal Recessive Inheritance（AR）

4.7 Sex-linked Inheritance

Summary

Exercises

Chapter 5 Mitochondrial Disorders

5.1 Unusual Forms of Inheritance-Matrilineal Inheritance

5.2 mtDNA

5.3 Mutation of Mitochondrial Gene

5.4 mtDNA Disorders

Summary

Exercises

Chapter 6 Polygenic or Multifactorial Inheritance

6.1 Polygenic Inheritance of Quantitative Traits

6.2 Characteristics of Polygenic Diseases

6.3 Polygenic Inheritance of Disease

6.4 Estimation of Recurrence Risks of Polygenic Diseases

Summary

Exercises

Chapter 7 Human Chromosomes

7.1 Human Chromosomes

7.2 Structure of Chromosomes

7.3 Classification of Chromosomes

7.4 Chromosome Analysis

7.5 X chromatin and Lyon Hypothesis

7.6 Telomere and Cancer

Summary

Exercises

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Chapter 8 Chromosomal Disorders

Chapter 9 Biochemical Genetics

Chapter 10 Diagnosis of Genetic Diseases

Chapter 11 Treatment of Genetic Diseases

Overall Review of Medical Genetics

Model Test

Standard Answer

Experimental Guidance of Medical Genetics

References